Improving lung cancer risk stratification leveraging whole transcriptome RNA sequencing and machine learning across multiple cohorts
- Journal
- BMC Medical Genomics · vol. 13 · no. Suppl 10 · pp. 151
- Published
- 22 Oct 2020
- PMID
- 33087128
- Record
- ↗ Journal record
Synopsis
The development paper for the RNA sequencing-based Percepta Genomic Sequencing Classifier, built with ensemble and hierarchical models across multiple cohorts. The final GSC model uses 1,232 genes and four clinical covariates: age, pack-years, inhaled medication use and specimen collection timing. Kennedy is fourteenth of sixteen authors.
In the career genome
- VeracyteChapter 09 · Strand B · ResearchVeracyte, Inc.
Percepta and Envisia
Chief Scientific Officer and Chief Medical Officer, Veracyte
APR 2015 – APR 2024